The temp I like to use for all around PvM (spawns, boss encounters, etc) is as follows (it also works ok for pvp while defending spawns):
120 Anatomy
91 Healing
120 Throwing
110 Tactics
100 Bushido
90 Chiv (120 from jewels)
89 Necromancy (99 from jewels)
Use 45 hci from items (+5 hci racial); set your stats so that after items/potions/petals you are 150 str/150 dex; on armor imbue: stamina increase so you're above 180, lots of mana increase, 40% lower mana cost, and lots of SSI (Breastplate of Berserker, Ranger's Cloak of Augmentation, Turquoise Ring, Always 30 ssi on soul glaive), and I use reforged luck pieces for that boost. Be sure to use your backpack wisely - trapbox, apples, potions, enhanced bandaids.
As far as weps go use appropriate slayer, hit mana leech, 30 ssi. Get karma up to +19,000 and Divine fury gives you an extra 15% ssi, damage increase boost, and hit chance increase boost.
Hope that helps, goodluck!