I started checking spawns again and I happened on a couple fellas doing despise. Being lazy and somewhat greedy I decided to protect them for some free scrolls.
When the champ died I noticed I had 2 of the new mastery things in my pack without having accepted ANY quest. So protection will guarantee you a drop at a mastery. At least in fel anyway. I've never done an ilsh spawn so i'll test protection there and post results.
Edit: Tested and no tram ruleset spawns allow protection.
