Wow, weird that damage is still so confusing...
100% from items + 200% from "specials" like slayer, EoO, etc.... = 300% cap (plus stat and skill bonus)
Tactics, Anatomy, Lumberjacking and Strength add to that, more specifically...
Tactics Damage Bonus = (120 / 1.6) + 6.25 = 81.25%
Anatomy Damage Bonus = (120 / 2) + 5 = 65%
Lumberjacking Damage Bonus = (100/5)+10 = 30%
Strength Damage Bonus = (125 * 0.3) + 5 = 42.5%
Items Damage Increase = 100%
Total for the "100% or Items" side = 318.75% of base damage
Effects include - Super Slayer Weapons (100%), Specific Slayer Weapons (200%), Enemy of One, Divine Fury, etc....
Now, the original question was "Will a slayer talisman work with a slayer weapon"?
*IF* the slayer weapon is a Specific Slayer Type, then NO it won't work with it because you have already capped out on the "effects" side at 200%.
I would assume the same to stand true regarding a specific slayer type of talisman.
That should be enough information to completely confuse people