OK, probably not a script problem as it is so wide spread.

But, I am having these issues on two different PCs at two different physical locations with two different OSs (XP and Vista).
The most recent problem is with Genesis' Auto Item Buyer. I read the posts on this site and the last 8 pages of posts on EUO site (until the release of 3.5). I did not find a similar issue: The buyer works for everything except actually buying. The menu opens and scrolls. The stats screen records gold spent, regs and bottles purchased. However, no gold is actually spent, no regs are purchased, and the buy menu shows nothing being purchased.
I recently had a problem with Twinkle McNugget's (very funny...the text replace) and Spewey's mining: no mining was ever done. Just recall from site to site. Once the scripts stopped working for a character they never worked again, even when restting spots (Twinkle McNugget's). I checked the spots manually, there is ore. After my 6th miner on the third shard stopped working I gave up.
Other issues include:
CyberPope's mining radar does not launch, no error, nothing
krustenkrabbe's SupplyShopper does not work. I used this for years, but it has been a while.